Bodybuilding And Steroids


Why Use Bulking Steroids to Bulk?

The answer to this question is: you don’t necessarily need to use bulking steroids to bulk for the reasons previously described. However, there lies plenty of convenience in utilizing bulking steroids that are traditionally very strong compounds, easy to acquire, and relatively inexpensive. Other reasons lie in perhaps the most important and most influential factor: the issue of the more dynamic aspects of the biochemistry rather than the core theory of hormonal action of how they work. What this specifically refers to is the issue of aromatization (the conversion of androgens into Estrogen), and all of the effects that come along with it, such as: water retention, possible fat gain/retention, and the addition of weight in the form of mass that is not muscle (mostly water). Such factors, which exist in almost all bulking steroids can actually be advantageous to an individual looking to bulk up and gain sheer mass and strength without much concern for body fat levels (within reason), or the less aesthetically pleasing effect of increased bloating and water retention.

The effects previously described stem from the result of aromatization, which is the process whereby some anabolic steroids will convert into Estrogen. The aromatization of androgens into Estrogen occurs with various anabolic steroids and not with others. The compounds that undergo moderate to high rates of aromatization tend to be traditionally used as bulking steroids, while those that are immune to aromatization will typically be utilized for other purposes (typically cutting, fat loss, and pre-contest). The aromatization associated with bulking steroids typically result in estrogenic effects such as water retention and non-muscle weight gain. The additional water weight retained by these bulking steroids can be beneficial for strength athletes, weight lifters, and bodybuilders when in bulking phases (or any athletes looking to make a particular weight class), but might be disadvantageous for speed athletes such as sprinters, due to the unnecessary weight gain that might slow them down.

Suffice to say, bodybuilders, strength athletes, and anyone typically looking to ‘bulk up’ represent the core users of bulking steroids. The additional water retention brought upon by the typical bulking steroids can be considered beneficial for many, as it can not only add to the amount of size and weight gained, but can also assist in providing a much fuller look to the muscles, aid in better contractions, and serve as a form of protection as the additional water is retained in and around connective tissue (tendons, joints, ligaments). Such a benefit is of importance to the big and strong heavy lifts that are typically engaged in during a bulk, though it should be noted that bulking steroids will generally provide rapid mass and strength gains that could possibly place excessive strain and stress on connective tissues. Users looking to utilize bulking steroidsshould heed this warning carefully, as a beginner anabolic steroid user engaging in a cycle that includes bulking steroids can possibly gain upwards of 20 – 30 pounds of mass within a matter of weeks, although a large portion of such gains would likely be water weight.

When Bulking Steroids Might Not Be Suitable

Aesthetically, the water gain from the use of bulking steroids might be a problem for those looking to maintain a ‘ripped’ lean physique, as the additional water retention will lend to the physique a soft and puffy look that will blur the definition of the muscles due to peripheral water retention. Hence, this is why competitive bodybuilders tend to utilize bulking steroids during the off-season training, when there is no requirement to achieve peak definition and body fat levels for a stage performance. Additionally, bulking steroids might not be preferable for those who wish to achieve smaller gains, or for those who wish to achieve strictly lean mass gains with minimal to no water or fat retention. Due to the estrogenic nature of bulking steroids, an element of lipogenesis (fat storage) or fat retention might be present. However, for those who wish to eliminate or reduce the incidence of water retention or fat retention/gain, the use of an aromatase inhibitor (such as Aromasin or Arimidex) during the cycle would be optimal. In such a situation, the aromatase inhibitor would inhibit the aromatase enzyme and prevent the anabolic steroid(s) from being aromatized into Estrogen, thereby eliminating water retention and other estrogenic side effects at the root cause. Note that the use of an aromatase inhibitor will do nothing for anabolic steroids that do not aromatize into Estrogen but are estrogenic in and of themselves, such as Anadrol (Oxymetholone).

The following is a list of the typically used and commonly considered bulking steroids (note that not all but most of the following are moderate to highly Estrogenic),

Anadrol (Oxymetholone)
Andriol (Testosterone Undecanoate)
Dianabol (Methandrostenolone)
Deca-Durabolin (Nandrolone Decanoate)
Equipoise (Boldenone Undecylenate)
Sustanon 250 (Testosterone blend)
Testosterone Cypionate
Testosterone Enanthate
Testosterone Propionate
Trenbolone Acetate
Trenbolone Enanthate
Trenbolone Hexahydrobenzylcarbonate (Parabolan)

Aug 5

Properties of Aromasin

Aromasin (Exemestane) belongs to a category and class of drugs known as aromatase inhibitors (AIs). Aromatase inhibitors belong to an even broader class of drugs known as anti-estrogens. The other subcategory of drug under the anti-estrogens classification is the selective estrogen receptor modulators (SERMs), such as Nolvadex and Clomid. AIs and SERMs make up anti-estrogens. Aromatase inhibitors differ greatly from SERMs in their action and how they deal with the issues of estrogen control.

Properties of Aromasin

Aromasin is extremely effective at 25mg daily for the reduction of serum circulating Estrogen levels in the body, as demonstrated earlier with its ability to reduce Estrogen by 85%. As with other second-line breast cancer treatments, Aromasin is so effective at inhibiting the aromatase enzyme (and thereby reducing Estrogen levels) that this compound is, like Arimidex, only administered to post-menopausal females, and/or utilized when other first-line treatments for breast cancer has failed. This is because post-menopausal females possess a very different shift in hormone levels and endocrine function in comparison to pre-menopausal females.

Arimidex and Letrozole are both classified as non-steroidal and non-suicidal aromatase inhibitors that compete with the substrate for binding to the enzyme active site. This is very different from Aromasin (Exemestane), which is a steroidal and suicidal aromatase inhibitor that acts as a mechanism-based steroidal inhibitor that mimics the substrate, is converted by the enzyme to a reactive intermediate, and results in the inactivation of the aromatase enzyme. For ease of understanding, what this means to the layman is that Aromasin’s chemical structure resembles the traditional ‘targets’ that aromatase binds to (Testosterone, for example) and that it essentially ‘fools’ the aromatase enzyme into binding with it, only to become inhibited/deactivated. Because the binding strength is so great, this inhibition becomes permanent for the aromatase enzyme that Aromasin has become bound to. Arimidex and Letro, being non-suicidal aromatase inhibitors, both compete with the enzyme’s traditional ‘targets’ rather than being assured a permanent spot (which is the advantage that Aromasin has over the other two).

Athletes, bodybuilders, and individuals engaging in the use of anabolic steroidswill favor the use of aromatase inhibitors such as Aromasin for their usefulness in reducing, mitigating, and avoiding Estrogenic side effects. These side effects are result of the aromatazation (or conversion) of aromatizable androgens (such as Testosterone) into Estrogen, which often results in far greater than normal physiological levels of Estrogen in the body. This is where the use of Aromasin (Exemestane) is very beneficial and highly favored among anabolic steroid using individuals, as Aromasin eliminates the issue of rising Estrogen levels at the root cause: By binding to and inhibiting/disabling the aromatase enzyme, supraphysiological levels of aromatizable androgens (such as Testosterone, Dianabol, Boldenone, etc.) cannot convert into Estrogen, thereby eliminating any possible risk of Estrogen-related side effects.


Clenbuterol is a bronchodilator designed to treat individuals who suffer from breathing disorders such as chronic asthma. While Clen, as it is commonly called shares some similarities to the popular Ephedrine medication Clenbuterol proves to be far more potent and effective in almost every way; not only as a bronchodilator but as a fat-loss medication as well. While Clenbuterol was developed for breathing disorder treatment it is in its fat-loss abilities for which it is most famous and through the years the use for this purpose has rapidly increased.

The Benefits of Clenbuterol

The benefits of Clenbuterol should be fairly easy to perceive as it will improve cardiovascular efficiency and our metabolic activity. While increasing lipolysis (fat-loss) will prove to be its greatest attribute its benefits do not end there. Clenbuterol has been shown to increase fat-free mass (lean tissue) although not to the degree of an anabolic steroid it will still carry a modest anabolic affect. This increase in fat-free mass, although modest is brought about by an increase in protein synthesis; this simply means your protein, the foundation of muscle tissue, is better served, its activity and efficiency becomes greater than without Clenbuterol being present in the body. Couple this with its strong fat-burning abilities, as increases in muscle tissue also increase metabolic activity you have one very powerful fat reducing medication on your hands.
The Side-Effects of Clenbuterol

As is with all medications, regardless of the form, Clenbuterol is not without the possibility of negative side-effects. While the side-effects will vary from person to person and can be controlled with responsible use they can be quite bothersome and problematic when they show. The most bothersome side-effect is due to this medications stimulating effect; many Clenbuterol users report a very jittery feeling and even insomnia when they take Clenbuterol; however, the extent can be very dose dependent. Another common side-effect is cramping but this appears to be even more individualistic than the jittery effect and can largely be eliminated by ensuring enough water is taken in every day.

There is one side-effect that goes beyond bothersome and into the realm of concern as Clenbuterol can be harsh on the heart through cardiac hypertrophy (the enlargement of ventricles.) However, again, this will be largely dose dependent and of little concern among those who use Clenbuterol responsibly. However, because this is a concern, in order to ensure we use responsibly Clenbuterol is not a medication we would want to use for fat-loss purposes for extended periods of time. We can safely and effectively use this medication for a decent amount of time but there is a right way and a wrong way but either way using this medication for the majority of a year could prove to be very damaging.
Clenbuterol Cycles & Doses:

There are generally two schools of thought on how to best utilize Clenbuterol safely and effectively. The most common method is 2 weeks on followed by two weeks off. While the 2wks on/2wks off is most common, increasingly a steady and longer duration of administration has increasingly become more popular.

    2wks on/2wks off: The idea is simple, start with a low dose and increase it every 2-3 days until you reach your maximum dose desired. Once you’re body begins to adapt discontinue use, wait two weeks and then begin again close to the dose you ended with or even with the exact dose; repeat as many times as necessary.
    Steady Use: Begin with a low dose and increase the dose slightly every 2-3 weeks as needed. Generally the increase will come in spurts of 20mcg and will continue to increase every 2-3 weeks until a desired level of fat-loss is achieved.

As you can see these are two very different methods of application and one emphatically works better than the other. While 2wks on/2wks off is the most popular it is only so due to the vast amount of misinformation thanks to the ever increasing phenomena known as “Bro Science” purported on a host of internet message boards. The truth is simple; the 2wk on/2wk off method is far less efficient than our other option. It is true, after a two week period your body will adjust to the stimulating effect and your jitters will dissipate largely but this does not mean the Clenbuterol is no longer working as is the common misconception. To obtain a full effect, although the immediate fat-loss will be greatest in the first two weeks we must continue Clenbuterol therapy far past the 2 week mark if we are to take full advantage of metabolic increasing activity. To achieve this end a steady increase in Clenbuterol every 2-3 weeks as needed will prove to be far more efficient. Most will find, both men and women that a starting dose of 40mcg per day to be perfect with increases of 20mcg every 2-3 weeks.

Fat Loss Steroids

Quite often anabolic androgenic steroids are placed in two classes; bulking steroids or fat loss steroids/cutting steroids. While either phrase largely implies the desire behind anabolic use it can often at times be a bit inaccurate. The fact of the matter is very simple, most anabolic androgenic steroids can achieve either purpose; while the primary purpose of many steroids can vary, most possess a level of both qualities including body fat reduction; varying to a degree. For example, there are certain steroids that are far better served for adding mass, steroids that are far better served for increasing strength or performance. The same can be applied to fat loss steroids; while anabolic androgenic steroids do not carry with them the primary purpose of burning fat some will do so in a secondary fashion to a higher degree. What we’ve done here is listed some of the most common questions, myths and often confused ideas and followed it with the absolute truth. By following this list you will have a much better understanding of the concept of fat burning steroids.

One of the most common reasons anyone uses anabolic androgenic steroids is for the purpose of leaning out and cutting up. With this being a common primary purpose there is a strong desire to ensure you’re using the best fat loss steroids available. Not only are the introduction to fat loss steroids important to you in achieving this purpose but so are the performance enhancing drugs (PED’s) you will add in addition.

Let’s be very clear on one important factor regarding anabolic androgenic steroids; while they may possess fat burning qualities none of them serve this primary purpose therefor none of them can be labeled fat loss steroids in a primary sense. Anabolic androgenic steroids largely serve four general primary purposes:

    Increasing Strength
    Increasing Muscle Mass
    Increasing Athletic Performance
    Increasing the “Hardness” of a Physique

While these are the primary purposes they will vary to a degree from one steroid to the next; some steroids serve one purpose more than another while others serve an entirely different primary function. Even so, a secondary characteristic of many can be fat burning and thereby it is these we may generally label fat loss steroids.
Increasing Fat Loss Steroids Abilities

While the primary purpose is not fat loss but a secondary function, additional non-steroidal drugs can greatly benefit and add to this effect. Of those belonging to the hormone class, without question the best hormone we can add as well as the best PED of all to serve this purpose is Human Growth Hormone (HGH.) Not only can HGH greatly increase fat burning but it can further make the steroids we use more effective including their secondary traits.

Other commonly used PED’s used in this purpose most largely include Clenbuterol (Clen) and Cytomel (T3.) While neither is a steroidal drug, the former being a bronchial medication and the latter a thyroid medication both can be positive additions to a cutting cycle and increase the amounts of fat lost. While neither of these will change the structure of function of the steroids used, in a sense, due to the mode of actions by each PED being used, including the steroids, by this mode of action when coupled together, our anabolics become stronger fat loss steroids.
How to Stack Fat Loss Steroids

In most cases you will need to build your cycle around testosterone; not only is testosterone an important part of most cycles it is all-around the most efficient and effective steroid known to man. Beyond testosterone there are many additional items we can add that may more or less fall into the fat loss steroids camp. Steroids such as Trenbolone and Stanozolol are always top choices, as can be Equipoise and Anavar. Beyond the steroids, effective fat burners as mentioned above are always a helpful tool in addition; cycles and stacks with these items, in conjunction with solid anabolic androgenic steroids and HGH will prove to be the ultimate fat burning machines.

Many faces of Tren

 ”Tren” could be referring to at least 5 different compounds:

1. Trenbolone Acetate - injectable version
2. Trenbolone Acetate - pellet form (Finaplix)
3. Trenbolone Cyclohexylmethylcarbonate
4. Trenbolone Hexahydrobencylcarbonate
5. Trenbolone Enanthate

The many names of tren have confused many people. One is actually not equivalent to the other. One common mistake is calling Trenbolone Hexahydrobencylcarbonate “Tren Enanthate.” They are similar, but not the same. People refer to Tren Acetate as Parabolan-wrong!

So, let’s clear this up.

The following is a brief summary of the main differences of each that was created in order to clear up confusion on tren and hopefully help others here in the process. It is not meant to provide a detailed description of Tren activity in the body.

1. Trenbolone Acetate—injectable version (Finaject and Finajet)
This is correctly referred to as “Fina.” Finaject is the acetate form of trenbolone. It was produced in a short acting ester (acetate), so its effect lasts only a short time and frequent administration is necessary. Finaject was an injectable steroid of veterinary medicine, which was extremely popular in bodybuilding and power lifting during the 1980’s. The injectable Trenbolone Acetate called Finaject is no longer produced.

2. Trenbolone Acetate—pellet form (Finaplix)
Finaplix was a veterinary cattle implant, which contained the potent androgenic steroid Trenbolone Acetate. Once Finaject and Finajet were nolonger manufactured, bodybuilders began using Finaplix to make topical or injectable versions of Trenbolone Acetate.

Today, cattle implants have become designer products with varied doses and combinations of estrogenic and/or androgenic (trenbolone) agents. So, the process of converting cattle implants to useful versions of trenbolone acetate has become more difficult since one must separate the trenbolone from the other additives present in the cattle implants before using it.

3. Trenbolone Cyclohexylmethylcarbonate
Parabolan contains a much different ester than Finaject and Finajet, called Trenbolone Cyclohexylmethylcarbonate. This ester extends the activity of trenbolone for more than two weeks, a more suitable design for human use.

The amount of trenbolone in 76 mg of Trenbolone Cyclohexylmethylcarbonate is equivalent to the amount of trenbolone in only 58 mg of Trenbolone Acetate. The acetate is a little more potent, more effective per milligram, because the acetate ester is lighter than the cyclohexylmethylcarbonate ester; therefore a higher percentage of the weight of Trenbolone Acetate is trenbolone. A similar comparison also can be made with the other long lasting esters of trenbolone: enanthate and hexahydrobenzylcarbonate.

The muscle building properties of Trenbolone Cyclohexylmethylcarbonate are the same as Trenbolone Acetate (Finaject or Finajet) except for the longer half-life.

Although it is very similar, this compound is NOT the same as Trenbolone Enanthate. The only difference in these compounds is the esters (see ester definitions below), which all act almost identically (long lasting esters).

4. Trenbolone Hexahydrobenzylcarbonate
Trenbolone Hexahydrobenzylcarbonate and Trenbolone Cyclohexylmethylcarbonate are exactly the same substances. Hexahydrobenzylcarbonate ester is just another name for cyclohexylmethylcarbonate ester.

5. Trenbolone Enanthate
Although it is very similar, this compound is NOT the same as Trenbolone Cyclohexylmethylcarbonate (Trenbolone Hexahydrobenzylcarbonate). The only difference in these compounds is the esters.


The most important difference between the esters is whether it is a short acting ester or a long lasting ester. The next most important difference is the weight of the ester. As mentioned under the Trenbolone Cyclohexylmethylcarbonate section (above), the relative potency of each ester of trenbolone is partially dependent on the weight of its ester.

The main difference between different esters is simply the number of carbon atoms in the ester. Propionate has three carbons, acetate has two, isobutyrate has four, enanthate has seven, cypionate has eight, and deaconate has ten. More unusual esters, such as cyclohexylmethylcarbonate (used in Parabolan) has eight carbons and one more oxygen than the above esters making it the heaviest.

Therefore, the esters of trenbolone in order of potency when compared milligram to milligram (from most potent to least):
1. Tren Acetate
2. Tren Enanthate
3. Tren Cyclohexylmethylcarbonate (Tren Hexahydrobenzylcarbonate)

The differences in potency caused by the esters are negligible. So, you should base your choice of Tren on how frequently you plan to inject, how much you trust your supplier, and how much you trust the brand of tren you purchase.

If you are concerned about the possible side effects of tren, and don’t mind frequent injections, then consider using Trenbolone Acetate. If bad side effects manifest, Tren Acetate will quickly leave your body after the last injection due to the short acting ester (acetate); and your body will be able to begin to recover quickly. On the contrary, your recovery from bad side effects won’t begin until 2 weeks after the last injection of a long lasting ester of tren because a long lasting ester of tren will stay active in your body for more than two weeks after your last injection—continuing to contribute to the bad side effects.

Jul 9

Gyno Prevention and Reversal

This will try to answer questions regarding gyno prevention and reversal, the use of Letrozole and other anti-estrogens. I will go over everything in very simple easy to understand language. Also we are talking about estrogen gyno here, not progesterone (but using letro will stop progesterone related problems as well since it inhibits all estrogen anyways). Progesterone gyno will be enlargement of your nipple area, the actual aereola, not a lump under it.

Let me make this first point very clear, as I state in my signature this is from my personal experience, so whether you agree with it or not is your own issue. I have helped many people with gyno and it has worked just fine for them as well.

To first understand why you are doing what you are doing I am going to go over a few things and a few definitions:

SERM - Selective estrogen Receptor Modulator. These drugs work by binding to the estrogen receptors and flooding them in a sense, making it difficult (but not impossible by any means) for estrogen to bind to the receptors and thus prevent the onset of estrogen related side effects.
Most common forms: Tamoxifen (Nolvadex), Clomiphene (clomid)
AI Aromatise Inhibitor. These drugs work by inhibiting the aromatization of estrogen. This means that in effect AI’s prevent androgens from converting to estrogen, again, making it difficult (but not impossible) for estrogen to reach receptor sites.
Most common forms: Anastrozole (l-dex, a-dex), Exemestane (Aromasin), FEMARA (Letrozole). For our purpose of reversing gyno we are interested in Letro.

Letro and your sex drive:
Letrozole will suppress your sex drive. This is another reason why it is so important to act on preventing gyno as soon as possible. Since we all know that Test should be run in every cycle this will cancel out the effect of sex drive suppression.

Running letro to prevent gyno:
If you decide to run estrogen protection while on cycle (and I suggest you do unless you are aware that you do not require it), you can run either a SERM or an AI. Letro will be the most powerful AI you can use, it will inhibit 98+% of estrogen using a dose as low as .25mg and even lower. This is why I suggest you do not use a dose higher than .50mg while on cycle just trying to prevent estrogen related side effects.

You will want to start running the letro approximately 2 weeks before you begin your cycle to allow it to fully stabilize in your blood. I have often heard the argument that letro takes up to 60 days to stabilize, I don’t know if I buy into this for the reason that I have reversed gyno after using letro for only 1 week. Still to be safe I recommend starting it before your cycle as stated above.

If you do decide to run letro there is absolutely no need to run another AI or SERM. Do not make the mistake of thinking more is better. Think of it this way; if letro is preventing the conversion of androgens to estrogen than there is no estrogen, what would the purpose of a SERM be when there is no estrogen to bind to the receptors? Nolva will only take away from the effectiveness of letro.

This brings me to my next point. Do not listen to anyone who tells you to bump up your Nolvadex to 60+mg ED if you get gyno. I have no idea where this idea started but I have seen it suggest far too many times recently. Nolvadex will do nothing to reverse your gyno - let me make that clear IT WILL DO NOTHING FOR gyno. If you are running nolva as your anti-E and start to develop gyno than sure you can bump the dosage a small amount to try to prevent it from progressing further, but Letrozole must begin ASAP.

It is very important that you begin taking Letrozole immediately, the longer your wait the more risk you take in not being able to reverse it.

How do I know if I have gyno?
If you have developed gyno you will have a lump behind your nipple. It will be fairly hard, and it will be tender to touch.

Running letro to reverse gyno:
I am going to go over the three different scenarios which people could fit into. Remember regardless of what scenario you are in it is important that you begin taking the letro ASAP.

1. Already using an anti-E aside from letro.
2. Already using letro @ a dose of .25mg or .50mg ED.
3. Not running any estrogen protection.

Day 1: .25mg Letro + anti-E*
Day 2: .50mg Letro
Day 3: 1.0mg Letro
Day 4: 1.5mg Letro
Day 5: 2.0mg Letro
Day 6: 2.5mg Letro **

Day 1: .50mg Letro
Day 2: 1.0mg Letro
Day 3: 1.5mg Letro
Day 4: 2.0mg Letro
Day 5: 2.5mg Letro **

Day 1: .50mg Letro
Day 2: 1.0mg Letro
Day 3: 1.5mg Letro
Day 4: 2.0mg Letro
Day 5: 2.5mg Letro **

*Regardless of the anti-E you are using it is important to still use it for the first day you begin letro as the letro will not have taken any effect and you by no means want your body to be without any protection when gyno is already prevalent.

** You will remain at this dose until gyno symptoms subside. Once you believe your gyno is gone it is important to stay at this dose for another 4-7 days to ensure all traces are gone. I recommend people with a bf% over 15 stay on for a week as it may be harder to judge completely whether the lump is completely gone. Once this period is over it will be important to taper letro down slowly rather than coming off it completely. Regardless of which manner you tapered up your dose you will all taper down in the same fashion.

Day 1: 2.0mg
Day 2: 1.5mg
Day 3: 1.0mg
Day 4: .50mg***
Day 5: .25mg
***You can remain at this dose or go down further to .25mg. It is really up to you at this point. They are both very common maintenance doses as an anti-E while on cycle. Personally I have stayed with .25mg and never had a problem.

Letro and the estrogen rebound:
With your estrogen being completely inhibited there is a definite estrogen rebound as your body tries to re-stabilize the testosterone :estrogen balance. We can prevent this rebound effect by supplementing further with another AI or SERM. So, I suggest that when you are coming to the end of your cycle you will more than likely be using Nolva in your PCT so just make sure that you begin taking nolva the last day you are going to take your letro and then continue on as you would with regular PCT.

This now leads us into the question of reversing gyno while not on cycle. There are a few things to remember here. You have already waited longer than you should have, and your sex drive will be shot. You can use tribulus or another natural test booster to help you in this scenario but I can’t guarantee the effectiveness. Just follow gyno reversal protocols 2 or 3. When coming off again you must taper and begin using Nolvadex to prevent any rebound effect that may occur.

How much Nolvadex should you use if you are not going into PCT and running this off cycle? I suggest starting at 20mg ED for a week and then lowering it to 10mg for another week and then coming off completely.

Jul 2

IGF-1 the Most Powerful Mediator of Muscle Growth

IGF-1 plays a crucial role in muscle regeneration. IGF-1 stimulates both proliferation and differentiation of stem cells in an autocrine-paracrine manner, although it induces differentiation to a much greater degree. IGF-1, when injected locally, increases satellite cell activity, muscle DNA, muscle protein content, muscle weight and muscle cross sectional area. The importance of IGF-1 lies in the fact that all of its apparent functions act to induce muscle growth with or without overload although it really shines as a growth promoter when combined with physical loading of the muscle.

IGF-1 also acts as an endocrine growth factor having an anabolic effect on distant tissues once released into the blood stream by the liver. IGF-1 possesses the insulin-like property of inhibiting degradation, but in addition can stimulate protein synthesis. The insulin-like effects are probably due to the similarity of the signaling pathways between insulin and IGF-1 following ligand binding at the receptors.

The ability of IGF-I to stimulate protein synthesis resembles the action of GH, which was shown in separate studies on volunteers to stimulate protein synthesis without affecting protein degradation. Although it is often believed that the effects of GH are mediated through IGF-1, this cannot be the case entirely. First, the effects of the two hormones are different, in that GH does not change protein degradation. Second, the effect of GH is observed with little or no change in systemic IGF-1 concentrations. Age related muscle loss has been prevented with GH injections, however it is believed that this is accomplished through IGF-1.

The results of this study are similar to other studies where IGF-1 was injected directly into muscle tissue, resulting in increases in size and strength of experimental animals. Using a virus as a genetic vehicle has an advantage over simply injecting the growth factor. The effects of a single viral treatment last significantly longer (months if not years) because the muscle cell itself is constantly overproducing its own IGF-1 from injected DNA.

The fact that the IGF-1 produced by the muscle of these mice did not reach the blood stream is interesting. Systemic injections of IGF-1 have not been successful in inducing this kind of anabolic effect in humans. In addition, IGF-1 produced by the liver is genetically different than that produced by muscle tissue. It could be that providing additional DNA for the muscle to produce it’s own IGF-1 is the key to achieving anabolic and rejuvenative effects specifically in skeletal muscle.
In this study there was a preferential preservation of type IIb muscle fibers in aging mice. These are the fibers most sensitive to muscle hypertrophy from training and they are also the first fibers to disappear with aging. In the mice receiving the engineered virus, there was also a preservation of the motor neuron, leading to an increase in functional capacity. It is speculated that age related muscle loss is secondary to the loss of neuronal activation of type-II fibers. By preventing the degeneration of typ-II motor units, functional capacity could be maintained into old age. This technique may also serve useful in the prevention of osteoporosis. Further study is necessary to determine wether IGF-1 is having an effect only on muscle fibers or on nervous tissues as well.

Finally, it was also exciting to see muscle growth in the young mice who received the injection (15% increase in muscle mass). This means that the injection provided levels of IGF-1 far and above what the muscle normally has access to and not simply a preservation of normal levels. Remember that this was not combined with exercise. The growth of the injected muscles happened even without an extreme mechanical stimulus. The mice were simply allowed to run around as they usually do. Because of these dramatic results, the authors expressed concern about the use of this technique to enhance performance or cosmetic appearance. Research Update is not my personal soap box so I won�t go off on the gender centered hypocrisy of cosmetic enhancement in our society. All we can hope for is that this technique will be used to treat more important diseases such as muscular dystrophy and thereby become somewhat available for other uses as well.

Short burst steroid cycles

One of the best approaches ever used to build muscle tissue is short burst steroid cycling. Short cycling can be implemented to what ever level you are, its not only for the advance Bodybuilder, it can be for all stages, its just the amount of steroid Mg is adjusted to suit the individual’s level. The best part of this thread will be aimed at advanced bodybuilders because of the high dose used with burst cycling but no discussion on dosages will be made on the open board unless it needs to be discussed.

Muscle tissue doesn’t grow continuously over long periods of time, weight gain and muscular growth doesn’t happen that way. Not in infants, toddlers, teenagers, or even weight trainers. Instead, weight gain seems to come in spurts or surges. It’s amazing how you can train hard and eat very well year round yet only seem to make progress in quick little infrequent spurts of growth even with taking all the AAS compounds the body still gets use to whats being taken and builds up tolerance and adapts. If you look back over your steroid cycle history you will notice the growth spurts within the cycles, we don’t keep on growing because if we did we would all be 500lbs+. This method can build huge tissue gains in that short growth window if everything is in place.

Pre -Cycle Primming- First you must open the growth window and create a very anabolic environment for muscle tissue to grow, muscle receptors will get very excitable and upgrade to except more glucose which will shift the muscle to fat ratio which in turn will create muscle tissue to build very quickly, when this is coupled with a short burst cycle right after a prime the results can be outstanding, some of you will understand this from rebound cycling after a comp, its very similar except the prime isn’t as harsh as the pre-cycle comp diet and the prime is only directed at creating and opening the growth window for the cycle, its a pre-cycle prime.(details of primming is in a separate thread).Hgh protocol should be ran during the prime at low dose and kicked up when cycle starts.

Duration - Short burst steroid cycling usually last for around 30 days, there is no set rule on the length of cycle and normally it can be open ended and stopped when growth slows/stops. You have to listen to the body and adjust, with burst cycling it shouldn’t be ran for long periods of time, longer doesn’t mean more or better gains.Keep it short and feed the growth window and build the tissue and stop, recover and maintain.

Dosages- The dose for a short burst cycle is alot more than you would normally use in a standard length steroid cycle, because of the prime and the body being in a very anabolic environment it can take on board alot more than usual and over loading androgens will fully push the body to grow, it also takes time for the body to adjust to the high level of hormones in relation to sides so before you are experiencing them your off cycle. Over your cycle history you would of tried the heavy dosages and seen the sides come and where its not worth the risk’s to muscle gain, this is why its kept to a short period before the body can adjust with sides the cycle is over and growth is completed. Individual dosages are designed off your cycle history, there is no set dose it all depends on what your cycle history looks like, someone who normally uses 500mg per wk will be completely different to the guy who uses 1500mgs per wk when designing short burst cycles, but both will have the benefit of using high amounts what they normally don’t run.

Side effects- If your looking for the best effective way to run hormones without to much negative feedback staying on for long periods of time probably isn’t the best option to take. Ive had far better blood work back from high burst cycles than when Ive ran longer cycles at alot less dosage. There is minimal impact on the HPTA and recovery is far easier than trying to bring back natural production from a long cycle, there is some elevated aggression because of the high amount of androgens but overall this can be channeled into your workouts. PCT should be painless and within normal boundaries of how you recover. Blood pressure in some can be a problem but not serious but needs to be checked throughout the period so aids can be used to combat the problem if needed. Water retention is low but can be elevated if this system is ran for long periods, but if there is a problem normal AI can be used to help this issue and OTC herbal diuretics. Tren user’s within this system get bad BW results due to the harshness of the compound but boy does it produce gains but you have to be prepared to have a hard recovery and sides, kinda defeats the object but again, down to the individual.

Compounds- Because its a short period of time the normal way would to run short ester’s, but you can use long ester’s within a short cycle, i know what some of you are thinking but it can be done with great results, because of the androgen overload your simply frontloading long ester’s to an amount were it is effective straight from the start, the only problem is you have to drop them out 14 days before the end and swap them with fast ester’s so everything is clear for PCT, i know what some are saying sounds pointless but its not, to the BB’s who prefer long ester and they respond better to them, remember its designed of your cycle history so if your better with long esters go with them until 14 days from the end and swap to fast ester’s, the daily injection and the amount of tissue the body can produce in a short period is amazing, if anyone wants to discuss long ester’s with this theory i will but at this moment in time i will stop before i complicate things more. Short ester’s and fast acting compounds are used and the exact compounds depends on what your trying to achieve but normally its Test based or what you respond best to, 2 /3 compounds are ran at a time but no need to run loads, keep them limited less is better,Ive even known guys used 1 compound with stunning results. HGH is increased to a high amount when cycle starts just like all the compounds. I did a study once with some BB’s and the dosages range alot with all different HGH protocol’s which is interesting reading but i can go into that at a later date.

Maintenance - Due to the HPTA being shut down or suppressed for a short period of time its far better to get it to respond when the cycle is over, remember being shut down for weeks on end cause’s serious issues about recovery and maintenance, shorter shut downs produces easier recovery no matter how much you have pushed in the body,which in turn results in better maintenance which equals keeping more gains. Once you have shut down your HPTA its down and its the period of shutdown what cause’s damage, would you rather shut down your HPTA for 14 weeks or 30 days?? or continually shutting down and recovering isn’t the other best approach either, depends on the person’s goals and what he wants to achieve with BBing, some of my friends who are at a high level use short burst cycling coupled with bridge’s because of what they have to compete with on stage and get ready for photo shoots nearly all the time. Recovering from a standard or long cycle it cost muscle tissue while trying to recovery even with all the peptide’s chemicals this day and age we still lose tissue, with this theory losing tissue is limited.

Diet - After the prime as been implemented correctly, the cycle should be started and this day should line up with the first high carb day after the low day carbs within the prime, calories from then on should be increased to over maintenance, different opinions here to how much, again down to knowing your body and how it responds, many who increase too fast will create huge water retention due to the increase of carbs, some don’t and over load can be implemented, if your one of these guys who has water retention when carbs are increased after being depleted then over maintenance should be ran for 1 week ish then, overload should be used, if your not and you don’t carry the water from the carbs increase calories well over maintenance and go with growth,also depends on how much of a prime as been ran!! feed the dramatic growth what can occur if you have done the procedure correctly.Over eat, over feed, overload on the first day of the cycle straight after the prime from low carb phase.One last thing and i hope many understand this- diet is 24hr dedication while running the theory.

Training - Train to how you grow, best advice here is heavy intense workouts to total failure,HIT style or what ever works for you, you have the answers on how you grow. Intense is the key, stimulation of the whole body to grow, don’t waste this time, remember to train how i am recommending is impossible for 10-12 weeks, its to hard and wouldn’t last 4 weeks, before a turn around is needed and lay up from the heavy training session, so with this in mind you can mentally focus on this because its only for around 30 days long. Ive used many ways myself but the best for me with this style of cycling was heavy drop sets to failure plus forced, swapped to pre-exhausted drop sets to failure the following next total body workout, then swapped again. Workouts are short but seriously intense but you have the food/chemicals and energy to support this for this short period so don’t waste it, Ive seen huge amounts of tissue build from this, myself i created 10lbs of clean tissue in a very short period of time after PCT and maintenance. Everybody’s different to how much they build and comes down to if you have primed correctly, designed the perfect stack for you, placed the correct amount of mg’s in the blood every day and how well you train to build fresh tissue.

When i was first learnt this method my whole body changed to a serious level,I never went back to the normal way of cycling, it suited me so much and the growth was amazing. Borreson sat me down and explained in detail how this can happen and to this day things have moved forward so much from Paul’s day but i always remember him saying “please try it you will be amazed” he was right and it could for you. Look at Dorian what he did straight after a show….he was back in the gym the day after while the other were on vacation, he was using the growth window to create a very anabolic environment for tissue to grow and he used it, thats why in some years he produced some serious muscle tissue gains what has been seen since due to his method and style, many top pro’s used this system but its tweaked to suit their individual’s needs.

Please note, i am not saying do short burst cycles with little time off and then back on short burst cycle, no i haven’t gone into that side of things, all i am doing is explaining the whole theory behind short burst cycling with first hand experience from myself and many bodybuilder’s.

Anadrol 50 - Increase Your Bulking Abilities

It’s time for a serious bulk cycle. You just competed in the bodybuilding open division for the first time, and let’s be honest- you just had your rear end handed to you by guys carrying a lot more muscle. It’s time to buckle down and spend a solid 9 months adding muscle to your frame. You’ve had your post-show food binge. You already retired then un-retired. You’ve spent the last 2 weeks moping with your face in a pizza box mulling over your next step. You gave your body a rest and now it’s time to come back, both barrels firing. Let’s add some mass!

This time, you’re going to do it right. You’re going to run a cycle using the very toxic, and very powerful Anadrol 50. It’s well known in steroid circles that the most effective steroids also deliver the most side effects, and you’re prepared for that. Let’s learn more about Anadrol and see if you’re ready for it.

Anadrol is one of the most powerful steroids. It will certainly help you gain lean muscle mass, that goes without saying. Your appetite will skyrocket, allowing you to eat more food. Your protein synthesis will increase, meaning you will be able to use more of the protein in your diet for muscle-building purposes. Your red blood cell count will increase, making you stronger and allowing you to possess more stamina. You’ll retain some water – which can be a good thing or a bad thing. In a way, this is good because it means you will be cushioning your joints, much larger and stronger, and able to move more weight, which will lead to a gain in muscle mass. At the same time, this water retention can also cause you to look and feel bloated. There are also the side effects of acne and potential liver damage. You don’t want to use Anadrol for your entire off-season. Rather, two small cycles of 8 weeks separated by a 12 week gap is preferable.

Anadrol has been out for almost 50 years, and remains popular despite all of the innovations in steroids that have arrived during this time. It is an oral drug, and is only active in the body for about 16 hours. It can be detected in steroid tests up to 2 months after use, a fact that should be considered when planning your pre-contest stack or participating in any tested powerlifting event.

Anadrol should be stacked with injectables in order to make the most possible gains in a short amount of time. Adding it to a cycle of testosterone and Nandrolone will leave you feeling superhuman, and will add some serious mass to your frame. It works in just about any bulking stack, so long as you give yourself enough food, training and rest to make the most of it. Anadrol is a fairly safe drug, despite the toxicity warnings, as long as it is used in moderation and breaks are taken. Give it a shot this off-season if you are very serious about gaining some new muscle mass.